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Research Paper

Vol. 7 No. 1 (2025): Continuous Flow

Nanoceramic materials for bone regeneration: a systematic review in animal experimental studies

DOI
https://doi.org/10.52466/ijamb.v7i1.139
Published
2025-01-01

Abstract

Nanoceramic materials re used for bone healing. However, the diversity of nanoceramics and the different manufacturing methods used in literature make results difficult to compare. In this context, the purpose of this study was to perform a literature systematic review examining the effects of different nanoceramic materials in bone healing. The search was performed according to Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) orientations and Medical Subject Headings (MeSH) descriptors: “bone tissue”, “nanomaterial”, “ceramic” and “animal studies”. 162 articles were retrieved from PubMed and Scopus databases. After elegibility analyses, 29 papers were included (covering a 2007 and 2020 period). Results demonstrated that the commonest materials were Hydroxiapatite, Bioglass, Ttricalcium Phosphate and Bicalcium Phosphate, alone or associated with other materials or drugs. In vivo results showed that nanoceramic materials promoted bone healing in different animals models. As conclusion, nanoceramic materials are excellent candidates as bone grafts due to their bioactivity and good bone interaction.

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